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Year Number of Results
2011 1
2012 1
2013 3
2014 4
2015 2
2018 1
2020 1
2021 1
2022 1
2023 2
2024 1

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16 results

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Page 1
Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements.
Luquette LJ, Miller MB, Zhou Z, Bohrson CL, Zhao Y, Jin H, Gulhan D, Ganz J, Bizzotto S, Kirkham S, Hochepied T, Libert C, Galor A, Kim J, Lodato MA, Garaycoechea JI, Gawad C, West J, Walsh CA, Park PJ. Luquette LJ, et al. Among authors: garaycoechea ji. Nat Genet. 2022 Oct;54(10):1564-1571. doi: 10.1038/s41588-022-01180-2. Epub 2022 Sep 26. Nat Genet. 2022. PMID: 36163278 Free PMC article.
Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner.
Wang M, Brandt LTL, Wang X, Russell H, Mitchell E, Kamimae-Lanning AN, Brown JM, Dingler FA, Garaycoechea JI, Isobe T, Kinston SJ, Gu M, Vassiliou GS, Wilson NK, Göttgens B, Patel KJ. Wang M, et al. Among authors: garaycoechea ji. Mol Cell. 2023 Jul 20;83(14):2417-2433.e7. doi: 10.1016/j.molcel.2023.05.035. Epub 2023 Jun 21. Mol Cell. 2023. PMID: 37348497 Free PMC article.
Pathological consequences of DNA damage in the kidney.
Garaycoechea JI, Quinlan C, Luijsterburg MS. Garaycoechea JI, et al. Nat Rev Nephrol. 2023 Apr;19(4):229-243. doi: 10.1038/s41581-022-00671-z. Epub 2023 Jan 26. Nat Rev Nephrol. 2023. PMID: 36702905 Review.
Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response.
Mulderrig L, Garaycoechea JI, Tuong ZK, Millington CL, Dingler FA, Ferdinand JR, Gaul L, Tadross JA, Arends MJ, O'Rahilly S, Crossan GP, Clatworthy MR, Patel KJ. Mulderrig L, et al. Among authors: garaycoechea ji. Nature. 2021 Dec;600(7887):158-163. doi: 10.1038/s41586-021-04133-7. Epub 2021 Nov 24. Nature. 2021. PMID: 34819667
Why does the bone marrow fail in Fanconi anemia?
Garaycoechea JI, Patel KJ. Garaycoechea JI, et al. Blood. 2014 Jan 2;123(1):26-34. doi: 10.1182/blood-2013-09-427740. Epub 2013 Nov 7. Blood. 2014. PMID: 24200684 Free article. Review.
Biocatalysed halogenation of nucleobase analogues.
Médici R, Garaycoechea JI, Dettorre LA, Iribarren AM, Lewkowicz ES. Médici R, et al. Biotechnol Lett. 2011 Oct;33(10):1999-2003. doi: 10.1007/s10529-011-0655-z. Epub 2011 Jun 10. Biotechnol Lett. 2011. PMID: 21660577
Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells.
Garaycoechea JI, Crossan GP, Langevin F, Mulderrig L, Louzada S, Yang F, Guilbaud G, Park N, Roerink S, Nik-Zainal S, Stratton MR, Patel KJ. Garaycoechea JI, et al. Nature. 2018 Jan 11;553(7687):171-177. doi: 10.1038/nature25154. Epub 2018 Jan 3. Nature. 2018. PMID: 29323295 Free PMC article.
Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen.
Pontel LB, Rosado IV, Burgos-Barragan G, Garaycoechea JI, Yu R, Arends MJ, Chandrasekaran G, Broecker V, Wei W, Liu L, Swenberg JA, Crossan GP, Patel KJ. Pontel LB, et al. Among authors: garaycoechea ji. Mol Cell. 2015 Oct 1;60(1):177-88. doi: 10.1016/j.molcel.2015.08.020. Epub 2015 Sep 24. Mol Cell. 2015. PMID: 26412304 Free PMC article.
16 results